RT Book, Section
A1 Gosser, Rena
A2 DiPiro, Joseph T.
A2 Yee, Gary C.
A2 Posey, L. Michael
A2 Haines, Stuart T.
A2 Nolin, Thomas D.
A2 Ellingrod, Vicki
SR Print(0)
ID 1182453332
T1 Drug-Induced Ophthalmic Disorders
T2 Pharmacotherapy: A Pathophysiologic Approach, 11e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260116816
LK accesspharmacy.mhmedical.com/content.aspx?aid=1182453332
RD 2024/04/23
AB KEY  CONCEPTS  The  eye  is  highly  susceptible  to  drug  toxicity  due  to  its  extensive  vasculature.  When  ophthalmic  disorders  occur,  all  medications  and  biologic  agents,  irrespective  of  route  of  administration,  are  potential  causes.  It  is  difficult  to  fully  quantify  the  incidence  of  drug-induced  ophthalmic  disorders  due  to  the  variety  of  causative  factors  and  side-effect  reporting  behaviors  of  clinicians.  The  most  common  drug-induced  ophthalmic  disorders  include  dry  eye,  cataract,  intraoperative  floppy  iris  syndrome,  optic  neuropathy,  and  retinopathy.  The  severity  of  drug-induced  ophthalmic  disorders  varies  and  depends  on  dose,  pharmacokinetics,  genetic  predisposition,  age,  extremes  of  body  weight,  and/or  duration  of  exposure.  Health  professionals  and  patients  should  discuss  potential  drug-induced  ophthalmic  disorders  to  ensure  awareness,  prompt  identification,  management,  and  treatment.