RT Book, Section A1 McQuaid, Kenneth R. A2 Katzung, Bertram G. A2 Vanderah, Todd W. SR Print(0) ID 1176472370 T1 Drugs Used in the Treatment of Gastrointestinal Diseases T2 Basic & Clinical Pharmacology, 15e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260452310 LK accesspharmacy.mhmedical.com/content.aspx?aid=1176472370 RD 2024/03/28 AB CASE STUDYA 21-year-old woman comes with her parents to discuss therapeutic options for her Crohn disease. She was diagnosed with Crohn disease 2 years ago, and it involves her terminal ileum and proximal colon, as confirmed by colonoscopy and small bowel radiography. She was initially treated with mesalamine and budesonide with good response, but over the last 2 months, she has had a relapse of her symptoms. She is experiencing fatigue, cramping, abdominal pains, and nonbloody diarrhea up to 10 times daily, and she has had a 15-lb weight loss.She has no other significant medical or surgical history. Her current medications are mesalamine 2.4 g/d and budesonide 9 mg/d. She appears thin and tired. Abdominal examination reveals tenderness without guarding in the right lower quadrant; no masses are palpable. On perianal examination, there is no tenderness, fissure, or fistula. Her laboratory data are notable for anemia and elevated C-reactive protein. What are the options for immediate control of her symptoms and disease? What are the long-term management options?