RT Book, Section
A1 Madoff, Lawrence C.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1177742381
T1 Parasitic Arthritis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1177742381
RD 2024/04/25
AB Arthritis  due  to  parasitic  infection  is  rare.  The  guinea  worm  Dracunculus  medinensis  may  cause  destructive  joint  lesions  in  the  lower  extremities  as  migrating  gravid  female  worms  invade  joints  or  cause  ulcers  in  adjacent  soft  tissues  that  become  secondarily  infected.  Hydatid  cysts  infect  bones  in  1–2%  of  cases  of  infection  with  Echinococcus  granulosus.  The  expanding  destructive  cystic  lesions  may  spread  to  and  destroy  adjacent  joints,  particularly  the  hip  and  pelvis.  In  rare  cases,  chronic  synovitis  has  been  associated  with  the  presence  of  schistosomal  eggs  in  synovial  biopsies.  Monarticular  arthritis  in  children  with  lymphatic  filariasis  appears  to  respond  to  therapy  with  diethylcarbamazine  even  in  the  absence  of  microfilariae  in  synovial  fluid.  Reactive  arthritis  has  been  attributed  to  hookworm,  Strongyloides,  Cryptosporidium,  and  Giardia  infection  in  case  reports,  but  confirmation  is  required.