RT Book, Section
A1 Conwell, Darwin L.
A1 Banks, Peter A.
A1 Greenberger, Norton J.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1177999708
T1 Acute Pancreatitis Pathogenesis and Diagnosis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1177999708
RD 2024/04/23
AB Recent  U.S.  estimates  from  the  Nationwide  Inpatient  Sample  report  that  acute  pancreatitis  is  the  most  common  inpatient  principal  gastrointestinal  diagnosis.  The  incidence  of  acute  pancreatitis  also  varies  in  different  countries  and  depends  on  cause  (e.g.,  alcohol,  gallstones,  metabolic  factors,  drugs  [Table  341-1]).  The  annual  incidence  ranges  from  13  to  45  cases  per  100,000  persons.  Acute  pancreatitis  results  in  >250,000  hospitalizations  per  year.  The  median  length  of  hospital  stay  is  4  days,  with  a  median  hospital  cost  of  $6096  and  a  mortality  of  1%.  The  estimated  cost  annually  approaches  $2.6  billion.  Hospitalization  rates  increase  with  age,  which  are  88%  higher  among  blacks,  and  are  higher  among  males  than  females.  The  age-adjusted  rate  of  hospital  discharges  with  an  acute  pancreatitis  diagnosis  increased  62%  between  1988  and  2004.  From  2000  to  2009,  the  rate  increased  30%.  Thus,  acute  pancreatitis  is  increasing  and  is  a  significant  burden  on  health  care  costs  and  resource  utilization.