RT Book, Section A1 Schwinghammer, Terry L. A1 DiPiro, Joseph T. A1 Ellingrod, Vicki L. A1 DiPiro, Cecily V. SR Print(0) ID 1178897119 T1 Endocarditis T2 Pharmacotherapy Handbook, 11e YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781260116694 LK accesspharmacy.mhmedical.com/content.aspx?aid=1178897119 RD 2024/03/28 AB Endocarditis is an inflammation of the endocardium, the membrane lining the chambers of the heart and covering the cusps of the heart valves. Infective endocarditis (IE) refers to infection of the heart valves by microorganisms, primarily bacteria.Endocarditis is often referred to as either acute or subacute depending on the clinical presentation. Acute bacterial endocarditis is a fulminating infection associated with high fevers, systemic toxicity, and death within days to weeks if untreated. Subacute infectious endocarditis is a more indolent infection, usually occurring in a setting of prior valvular heart disease.