RT Book, Section A1 Schwinghammer, Terry L. A1 DiPiro, Joseph T. A1 Ellingrod, Vicki L. A1 DiPiro, Cecily V. SR Print(0) ID 1178898536 T1 Opioid Use Disorder T2 Pharmacotherapy Handbook, 11e YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781260116694 LK accesspharmacy.mhmedical.com/content.aspx?aid=1178898536 RD 2024/04/24 AB Opioid use disorder (OUD) consists of intoxication and withdrawal from the substance for which there is no cure. Since 1999, the number of overdose deaths contributed to OUD has more than tripled. These deaths have involved opioid substances including prescription opioids (ie, natural opioids, semisynthetic opioids, and methadone), as well as heroin and synthetic opioids (ie, illicitly manufactured fentanyl).