RT Book, Section A1 Cantrell, Matthew A1 Vouri, Scott Martin A1 Dyson, Tess E. A2 Sutton, S. Scott SR Print(0) ID 1179736293 T1 Urology T2 McGraw Hill’s NAPLEX® Review Guide, 4e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781264258062 LK accesspharmacy.mhmedical.com/content.aspx?aid=1179736293 RD 2024/03/29 AB Benign prostatic hyperplasia (BPH) is an enlarged prostate gland. The prostate gland surrounds the urethra, the tube that carries urine from the bladder out of the body. As the prostate gets bigger, it may squeeze or partly block the urethra causing problems with urinating. The prostate begins to grow as men age, increasing the risk for BPH. Patients with BPH have increased smooth muscle tissue in the prostate containing α1-adrenergic receptors resulting in vasoconstriction and narrowing of the urethral lumen. Additionally, patients have physical obstruction symptoms resulting from an enlarged prostate.