RT Book, Section
A1 Katzung, Bertram G.
A1 Kruidering-Hall, Marieke
A1 Tuan, Rupa Lalchandani
A1 Vanderah, Todd W.
A1 Trevor, Anthony J.
SR Print(0)
ID 1180557569
T1 Gonadal Hormones & Inhibitors
T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 13e
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260117127
LK accesspharmacy.mhmedical.com/content.aspx?aid=1180557569
RD 2024/04/20
AB The  gonadal  hormones  include  the  steroids  of  the  ovary  (estrogens  and  progestins)  and  testis  (chiefly  testosterone).  Because  of  their  extensive  use  as  contraceptives  and  replacement  therapy,  many  synthetic  estrogens  and  progestins  have  been  produced.  Related  agents  include  synthesis  inhibitors,  receptor  antagonists,  and  some  drugs  with  mixed  effects  (ie,  agonist  effects  in  some  tissues  and  antagonist  effects  in  other  tissues).  Mixed  agonists  with  estrogenic  effects  are  called  selective  estrogen  receptor  modulators  (SERMs).  Synthetic  androgens,  including  those  with  anabolic  activity,  are  also  available  for  clinical  use.  A  diverse  group  of  drugs  with  antiandrogenic  effects  is  used  in  the  treatment  of  prostate  cancer  and  benign  prostatic  hyperplasia  in  men  and  androgen  excess  in  women.  Some  gonadal  hormones  are  also  produced  in  the  adrenal  cortex.