RT Book, Section A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke A1 Tuan, Rupa Lalchandani A1 Vanderah, Todd W. A1 Trevor, Anthony J. SR Print(0) ID 1180558692 T1 Clinical Pharmacology of the Antihelminthic Drugs T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 13e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260117127 LK accesspharmacy.mhmedical.com/content.aspx?aid=1180558692 RD 2024/03/29 AB Helminths (worms) are multicellular parasites; they infect very large numbers of humans and cause a broad range of diseases.Antihelminthic drugs have diverse chemical structures, mechanisms of action, and properties. Many act against specific parasites, and few are devoid of significant toxicity to host cells. In addition to the direct toxicity of the drugs, reactions to dead and dying parasites may cause serious toxicity in patients. In the text that follows, the drugs are divided into three groups on the basis of the type of helminth primarily affected (nematodes, trematodes, and cestodes). The drugs of choice and alternative agents for selected important helminthic infections are listed in Table 53–1.