RT Book, Section A1 Lloyd-Jones, Donald M. A1 McKibbin, Kathleen M. A2 Loscalzo, Joseph A2 Fauci, Anthony A2 Kasper, Dennis A2 Hauser, Stephen A2 Longo, Dan A2 Jameson, J. Larry SR Print(0) ID 1197334883 T1 Promoting Good Health T2 Harrison's Principles of Internal Medicine, 21e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264268504 LK accesspharmacy.mhmedical.com/content.aspx?aid=1197334883 RD 2024/04/24 AB Prevention of acute and chronic diseases before their onset has been recognized as one of the hallmarks of excellent medical practice for centuries and is now used as a metric for highly functioning health care systems. The ultimate goal of preventive strategies is to avoid premature death. However, as longevity has increased dramatically worldwide over the last century (largely as a result of public health practices), increasing emphasis is placed on prevention for the purpose of preserving quality of life and extending the health span, not just the life span. Given that all patients will eventually die, the goal of prevention ultimately becomes compression of morbidity toward the end of the life span; that is, reduction of the amount of burden and time spent with disease prior to dying. As shown in Fig. 2-1, normative aging tends to involve a steady decline in the stock of health, with accelerating decline over time. Successful prevention offers the opportunity both to extend life and to extend healthy life, thus “squaring the curve” of health loss during aging.