RT Book, Section A1 Stringer, Janet L. SR Print(0) ID 1187634260 T1 Antifungal Drugs T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 6e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264264841 LK accesspharmacy.mhmedical.com/content.aspx?aid=1187634260 RD 2024/03/29 AB Fungi are eukaryotes, making it challenging to target the pathogen without significant host toxicity. In addition, many fungal infections occur in poorly vascularized tissues or avascular structures such as the superficial layer of the skin, nails, and hair. Fungi are slow growing and are, therefore, more difficult to kill than bacteria, where cell division can be a target. Because many fungi are opportunistic, host factors play an important role in determining prognosis. The antifungal agents essentially assist the host immune system with the fight against the fungus.