RT Book, Section A1 Dhaval K., Shah A1 Zhe, Li A1 Donald E., Mager A2 Ducharme, Murray P. A2 Shargel, Leon SR Print(0) ID 1188767572 T1 Targeted Drug Delivery Systems and Biotechnology Products T2 Shargel and Yu's Applied Biopharmaceutics and Pharmacokinetics, 8e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781260142990 LK accesspharmacy.mhmedical.com/content.aspx?aid=1188767572 RD 2024/03/28 AB Describe basic classification categories of protein therapeutics and discuss example drugs in each group.Compare and contrast the general pharmacokinetic characteristics of small-molecule and biological drugs.Describe the unique targeting mechanisms of monoclonal antibodies and novel antibody-based constructs along with general determinants of their disposition and effects.Identify the need and rationale for drug carriers and formulations for biologics along with the major components of targeted drug delivery systems.Recognize integrating and non-integrating delivery vectors that address disposition challenges and enable effective gene therapies.Describe the major processes governing the pharmacokinetic properties of biopharmaceuticals.