RT Book, Section
A1 Wight, Kayleigh
A1 Colucci, Philippe
A1 Ducharme, Murray P.
A2 Ducharme, Murray P.
A2 Shargel, Leon
SR Print(0)
ID 1188767807
T1 One-Compartment Open Model: Intravenous Bolus Administration
T2 Shargel and Yu's Applied Biopharmaceutics and Pharmacokinetics, 8e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781260142990
LK accesspharmacy.mhmedical.com/content.aspx?aid=1188767807
RD 2024/04/19
AB Discuss  the  clinical  relevance  of  IV  bolus  injection  and  introduce  concepts  of  the  one-compartment  linear  model  with  this  route  of  administration.Define  volume  of  distribution,  elimination  rate  constant,  and  clearance,  and  explain  how  to  calculate  these  parameters  in  a  one-compartment  linear  model  with  IV  bolus  injection.Explain  the  clinical  utility  of  the  one-compartment  model