RT Book, Section A1 Bowers, Dana R. A1 Tam, Vincent H. A2 Ducharme, Murray P. A2 Shargel, Leon SR Print(0) ID 1188770976 T1 Application of Pharmacokinetics to Clinical Situations T2 Shargel and Yu's Applied Biopharmaceutics and Pharmacokinetics, 8e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781260142990 LK accesspharmacy.mhmedical.com/content.aspx?aid=1188770976 RD 2024/03/28 AB Define Medication Therapy Management (MTM) and explain how MTM can improve the success of drug therapy.Explain what “critical-dose drugs” are and name an example.Define therapeutic drug monitoring and explain which drugs should be monitored through a therapeutic drug monitoring service.Calculate a drug dosage regimen in an individual patient for optimal drug therapy for a drug that has complete pharmacokinetic information and for a drug that has incomplete pharmacokinetic information.Explain the relationship of changing the dose and/or the dosing interval on the Cmax(ss), Cmin(ss), and Cav(ss).Define drug–drug interactions and the mechanisms of drug–drug interactions, and provide examples.Define population pharmacokinetics and explain how population pharmacokinetics enables the estimate of pharmacokinetic parameters from relatively sparse data obtained from study subjects.