RT Book, Section
A1 Preston, R. Julian
A1 Hoffmann, George R.
A2 Klaassen, Curtis D.
A2 Watkins, John B.
SR Print(0)
ID 6481339
T1 Chapter 9. Genetic Toxicology
T2 Casarett & Doull's Essentials of Toxicology, 2e
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-162240-0
LK accesspharmacy.mhmedical.com/content.aspx?aid=6481339
RD 2024/04/25
AB Genetic  toxicology  assesses  the  effects  of  chemical  and  physical  agents  on  the  hereditary  material  (DNA)  and  on  the  genetic  processes  of  living  cells.Oncogenes  are  genes  that  stimulate  the  transformation  of  normal  cells  into  cancer  cells.Genetic  toxicology  assays  serve  to  identify  mutagens  for  purposes  of  hazard  identification,  and  to  characterize  dose–response  relationships  and  mutagenic  mechanisms.A  broad  range  of  short-term  assays  for  genetic  toxicology  serve  to  identify  many  mutagens  and  address  the  relationship  between  mutagens  and  cancer-causing  agents.