RT Book, Section A1 Bauer, Larry A. A2 Bauer, Larry A. SR Print(0) ID 3517398 T1 Chapter 11. Carbamazepine T2 Applied Clinical Pharmacokinetics, 2e YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-147628-7 LK accesspharmacy.mhmedical.com/content.aspx?aid=3517398 RD 2024/04/25 AB Carbamazepine is an iminostilbene derivative related to the tricyclic antidepressants that is used in the treatment of tonic-clonic (grand mal), partial or secondarily generalized seizures (Table 11-1).1,2 Although methods have been suggested to treat acute seizures with carbamazepine, lack of an intravenous dosage form has limited its use in this area. Thus, the drug is used primarily as a prophylactic agent in the chronic therapy of epilepsy. Carbamazepine is also a useful agent to treat trigeminal neuralgia and bipolar affective disorders.2,3