RT Book, Section A1 Sutton, S. Scott A1 Hall, Philip D. A1 Norris, LeAnn B. A1 Bennett, Charles L. A2 Sutton, S. Scott SR Print(0) ID 7250785 T1 Chapter 11. Immune System T2 McGraw-Hill's NAPLEX® Review Guide YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-175562-7 LK accesspharmacy.mhmedical.com/content.aspx?aid=7250785 RD 2024/04/19 AB The immune system protects the body from invading pathogens and has an amazing ability to evolve and adapt based upon environmental exposure. The immune system is designed to attack and destroy foreign antigens/pathogens; however, the immune system must be able to distinguish self from nonself. Failure to differentiate self from nonself may lead to autoimmune diseases1 (see Table 11-1 for a list of autoimmune diseases). The immune system includes two functional divisions: (1) innate or nonspecific and (2) adaptive or specific.2, 3 The body uses the innate and adaptive immune responses to kill foreign pathogens. The greatest differences between the responses are in specificity and memory. The adaptive immune response can evolve with each subsequent infection, whereas the innate immune response stays the same with each infection.2, 3 Awareness of immune systems components and consequences of disrupting homeostasis must be understood in order to appropriately dose, administer, and monitor effects of medications given to manipulate immune responses.