RT Book, Section A1 Kerr, Jessica L. A2 Sutton, S. Scott SR Print(0) ID 7255301 T1 Chapter 58. Diabetes Mellitus T2 McGraw-Hill's NAPLEX® Review Guide YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-175562-7 LK accesspharmacy.mhmedical.com/content.aspx?aid=7255301 RD 2024/04/18 AB Diabetes mellitus is a progressive disease that affects nearly 8% of the US population.1 Diabetes affects patients of all ages and is associated with chronic complications of microvascular, macrovascular, and neuropathic disorders. There are two major types of diabetes: type 1 (T1DM) and type 2 (T2DM). Other subclasses have been identified such as gestational diabetes (GDM) and secondary diabetes associated with hormonal syndromes, medications, diseases of the pancreas, and rare conditions involving insulin receptors.2 Diabetes is characterized by hyperglycemia due to defects in insulin action, insulin secretion or both. The key differences between T1DM and T2DM are the pathophysiology, etiology of hyperglycemia, and clinical presentation.