RT Book, Section
A1 Cantrell, Matthew A.
A1 Kelly, Michael
A1 Vouri, Scott M.
A2 Sutton, S. Scott
SR Print(0)
ID 7256161
T1 Chapter 63. Urology
T2 McGraw-Hill's NAPLEX® Review Guide
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-175562-7
LK accesspharmacy.mhmedical.com/content.aspx?aid=7256161
RD 2024/04/19
AB The  prostate  is  a  small  male  organ  weighing  approximately  15  to  20  g  located  inferior  to  the  bladder  and  surrounds  the  urethra.  It  produces  fluid  which  contributes  to  ejaculate  volume,  but  may  also  prevent  infectious  processes  as  this  fluid  has  concentrated  quantities  of  zinc.1  As  men  age,  the  prostate—under  the  influence  of  androgenic  hormones—may  begin  to  grow  which  increases  risk  for  benign  prostatic  hyperplasia  (BPH).  BPH  is  the  most  common  urological  condition  in  aging  men  with  histological  evidence  of  its  presence  approaching  90%  in  octogenarians.2,3  Patients  with  BPH  often  have  increased  smooth  muscle  tissue  in  the  prostate  containing  α1-adrenergic  receptors  resulting  in  vasoconstriction  and  subsequent  narrowing  of  the  urethral  lumen.  Patients  may  also  have  symptoms  of  physical  obstruction,  resulting  from  an  enlarged  prostate.