RT Book, Section
A1 Trevor, Anthony J.
A1 Katzung, Bertram G.
A1 Kruidering-Hall, Marieke M.
A1 Masters, Susan B.
SR Print(0)
ID 56983327
T1 Chapter 40. Gonadal Hormones & Inhibitors
T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 10e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-178923-3
LK accesspharmacy.mhmedical.com/content.aspx?aid=56983327
RD 2024/04/19
AB The  gonadal  hormones  include  the  steroids  of  the  ovary  (estrogens  and  progestins)  and  testis  (chiefly  testosterone).  Because  of  their  importance  as  contraceptives,  many  synthetic  estrogens  and  progestins  have  been  produced.  These  include  synthesis  inhibitors,  receptor  antagonists,  and  some  drugs  with  mixed  effects  (ie,  agonist  effects  in  some  tissues  and  antagonist  effects  in  other  tissues).  Mixed  agonists  with  estrogenic  effects  are  called  selective  estrogen  receptor  modulators  (SERMs).  Synthetic  androgens,  including  those  with  anabolic  activity,  are  also  available  for  clinical  use.  A  diverse  group  of  drugs  with  antiandrogenic  effects  is  used  in  the  treatment  of  prostate  cancer  and  benign  prostatic  hyperplasia  in  men  and  hyper-androgenism  in  women.