RT Book, Section A1 Trevor, Anthony J. A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke M. A1 Masters, Susan B. SR Print(0) ID 56984639 T1 Chapter 53. Antihelminthic Drugs T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 10e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-178923-3 LK accesspharmacy.mhmedical.com/content.aspx?aid=56984639 RD 2024/03/28 AB Antihelminthic drugs have diverse chemical structures, mechanisms of action, and properties. Most were discovered by empiric screening methods. Many act against specific parasites, and few are devoid of significant toxicity to host cells. In addition to the direct toxicity of the drugs, reactions to dead and dying parasites may cause serious toxicity in patients. In the text that follows, the drugs are divided into 3 groups on the basis of the type of helminth primarily affected (nematodes, trematodes, and cestodes). The drugs of choice and alternative agents for selected important helminthic infections are listed in Table 53–1.