RT Book, Section A1 Hughes, Darrel W. A1 Attridge, Rebecca L. A2 Attridge, Rebecca L. A2 Miller, Monica L. A2 Moote, Rebecca A2 Ryan, Laurajo SR Print(0) ID 57285942 T1 Chapter 5. Advanced Cardiac Life Support T2 Internal Medicine: A Guide to Clinical Therapeutics YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-174580-2 LK accesspharmacy.mhmedical.com/content.aspx?aid=57285942 RD 2024/04/18 AB 4 rhythms produce pulseless cardiac arrest: ventricular fibrillation (VF), pulseless ventricular tachycardia (VT), pulseless electrical activity (PEA), & asystoleKey elements to survival (chain of survival) in patient with cardiac arrest (JAMA 1984;251:1723) Early access; early cardiopulmonary resuscitation (CPR): compressions, airway, breathing (CAB) (Circulation 2010; 122:S250); early defibrillation (10% ↓ in successful intervention for every 1min delay); early advanced cardiac life support (ACLS)Other elements associated with survival Location of cardiac arrest: in-hospital > community (3–4-fold delay in initiation of pharmacotherapy for community cardiac arrest); witnessed > unwitnessedInitial cardiac rhythmPreexisting medical conditionsAdult cardiopulmonary arrest usually results from an arrhythmia secondary to thrombosis or pulmonary embolismGoals of ACLS: sustained return of spontaneous circulation (ROSC), limiting end-organ damage, survival to hospital dischargeRole of drug therapy: enhance chance of ROSC, facilitate defibrillationPrompt delivery of CPR followed by defibrillation ↑ survival in patients with pulseless VT/VF