RT Book, Section
A1 Barthol, Colleen
A1 Gamboa, Conrado
A2 Attridge, Rebecca L.
A2 Miller, Monica L.
A2 Moote, Rebecca
A2 Ryan, Laurajo
SR Print(0)
ID 57296236
T1 Intrathecal Injections
T2 Internal Medicine: A Guide to Clinical Therapeutics
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-174580-2
LK accesspharmacy.mhmedical.com/content.aspx?aid=57296236
RD 2024/04/25
AB Table  Graphic  Jump  LocationTable  C-1  Adult  Intrathecal  Analgesic  Injections*View  Table||Download  (.pdf)Table  C-1  Adult  Intrathecal  Analgesic  Injections*ClassMedicationUsual  DoseOnsetDurationConcentrationSide  EffectsOpioid  AnalgesicsFentanyl5–25mcg/dose5–10min1–4h0.05mg/mL  PFSedation,  N/V,  urinary  retention,  respiratory  depression,  constipationHydromorphone50–100mcg/dose††10mg/mL  PFSedation,  N/V,  pruritus,  urinary  retention,  respiratory  depression,  constipationMorphine0.2–1mg/dose  (APS  recommends  0.1–0.3mg/dose)45–75min18–24h0.5,  1,  10,  25mg/mL  PFSedation,  N/V,  pruritus,  urinary  retention,  respiratory  depression,  constipationSedativesMidazolam1–2mg/dose5–10min2–4h1,  5mg/mL  PF  (diluted  to  max  conc  1mg/mL)Sedation,  motor  weakness,  respiratory  depressionNonopioid  AdjuvantsBaclofen25–75mcg/dose30–60min4–8h0.05,  0.5,  2mg/mL  PFSedation,  cognitive  impairment,  weakness,  hypotension,  constipation,  urinary  retentionClonidine25–75mcg30–60min6–8h100,  500mcg/mL  PFOrthostatic  hypotension,  bradycardia,  sedation