RT Book, Section A1 Lehman-McKeeman, Lois D. SR Print(0) ID 1100085093 T1 Absorption, Distribution, and Excretion of Toxicants T2 Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e YR 2012 FD 2012 PB McGraw-Hill Education PP New York, NY SN 978-0-07-176925-9 LK accesspharmacy.mhmedical.com/content.aspx?aid=1100085093 RD 2024/10/15 AB IntroductionCell MembranesPassive TransportSimple DiffusionFiltrationSpecial TransportActive TransportFacilitated DiffusionXenobiotic TransportersAdditional Transport ProcessesAbsorptionAbsorption of Toxicants by the Gastrointestinal TractAbsorption of Toxicants by the LungsGases and VaporsAerosols and ParticlesAbsorption of Toxicants Through the SkinAbsorption of Toxicants After Special Routes of AdministrationDistributionVolume of DistributionStorage of Toxicants in TissuesPlasma Proteins as Storage DepotLiver and Kidney as Storage DepotsFat as Storage DepotBone as Storage DepotBlood–Brain BarrierPassage of Toxicants Across the PlacentaRedistribution of ToxicantsExcretionUrinary ExcretionFecal ExcretionNonabsorbed IngestaBiliary ExcretionExhalationOther Routes of EliminationCerebrospinal FluidMilkSweat and SalivaComputational and Experimental Approaches to Assess Xenobiotic DispositionAbsorptionHepatobiliary ExcretionConclusion