RT Book, Section A1 Rogers, John M. SR Print(0) ID 1100086926 T1 Developmental Toxicology T2 Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e YR 2012 FD 2012 PB McGraw-Hill Education PP New York, NY SN 978-0-07-176925-9 LK accesspharmacy.mhmedical.com/content.aspx?aid=1100086926 RD 2024/03/28 AB HistoryScope of Problem: The Human ExperienceThalidomideDiethylstilbestrolEthanolTobacco SmokeCocaineRetinoidsAntiepileptic DrugsAngiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor AntagonistsPrinciples of Developmental ToxicologyCritical Periods of Susceptibility and Endpoints of ToxicityDose–Response Patterns and the Threshold ConceptMechanisms and Pathogenesis of Developmental ToxicityAdvances in the Molecular Basis of DysmorphogenesisPharmacokinetics and Metabolism in PregnancyRelationships between Maternal and Developmental ToxicityMaternal Factors Affecting DevelopmentGeneticsDiseaseNutritionStressPlacental ToxicityMaternal ToxicityDevelopmental Toxicity of Endocrine-Disrupting ChemicalsLaboratory Animal EvidenceHuman EvidenceImpact on Screening and Testing ProgramsModern Safety AssessmentRegulatory Guidelines for In Vivo TestingMultigeneration TestsChildren’s Health and the Food Quality Protection ActAlternative Testing StrategiesEpidemiologyConcordance of DataElements of Risk AssessmentNew ApproachesThe Benchmark-Dose ApproachBiologically Based Dose–Response ModelingPathways to the Future