RT Book, Section
A1 Funk, Janet L.
A2 Hammer, Gary D.
A2 McPhee, Stephen J.
SR Print(0)
ID 1100862517
T1 Disorders of the Endocrine Pancreas
T2 Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-180600-8
LK accesspharmacy.mhmedical.com/content.aspx?aid=1100862517
RD 2024/04/20
AB Insulin  and  glucagon,  the  two  key  hormones  that  orchestrate  fuel  storage  and  utilization,  are  produced  by  the  islet  cells  in  the  pancreas.  Islet  cells  are  distributed  in  clusters  throughout  the  exocrine  pancreas.  Together,  they  comprise  the  endocrine  pancreas.  Diabetes  mellitus,  a  heterogeneous  disorder,  is  the  most  common  disease  of  the  endocrine  pancreas.  Affecting  8%  of  the  world’s  adult  population  in  2011,  the  prevalence  of  diabetes  continues  to  increase  worldwide,  having  already  more  than  doubled  over  the  past  3  decades.  Pancreatic  tumors  secreting  excessive  amounts  of  specific  islet  cell  hormones  are  far  less  common,  but  their  clinical  presentations  underscore  the  important  regulatory  roles  of  each  hormone.