RT Book, Section A1 Smith, Silas W. A1 Howland, Mary Ann A2 Hoffman, Robert S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Nelson, Lewis S. A2 Goldfrank, Lewis R. SR Print(0) ID 1108421280 T1 Antidotes in Depth T2 Goldfrank's Toxicologic Emergencies, 10e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071801843 LK accesspharmacy.mhmedical.com/content.aspx?aid=1108421280 RD 2024/04/20 AB Activated charcoal (AC) is an excellent nonspecific adsorbent. Understanding AC's role in poison management is established by the integration of pharmacologic data, controlled volunteer trials, studies in heterogeneous patients with overdose or poisoning, and clinical experience.24 AC should be considered for a poisoned or overdosed patient after a risk-to-benefit assessment of the presumed ingested substance and patient-specific factors and circumstances.11 Benefits include preventing absorption or enterohepatic recirculation of a potentially toxic xenobiotic; risks include vomiting and subsequent aspiration pneumonitis. A detailed discussion of the merits of AC as a decontamination strategy is presented in Chap. 8.