RT Book, Section
A1 Gold, Jeffrey A.
A1 Nelson, Lewis S.
A2 Hoffman, Robert S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Nelson, Lewis S.
A2 Goldfrank, Lewis R.
SR Print(0)
ID 1108432874
T1 Ethanol Withdrawal
T2 Goldfrank's Toxicologic Emergencies, 10e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071801843
LK accesspharmacy.mhmedical.com/content.aspx?aid=1108432874
RD 2024/04/18
AB The  medical  problems  associated  with  alcoholism  and  alcohol  withdrawal  were  initially  described  by  Pliny  the  Elder  in  the  first  century  B.C.  In  his  work  Naturalis  Historia,  the  alcoholic  and  alcohol  withdrawal  were  described  as  follows:  “…drunkenness  brings  pallor  and  sagging  cheeks,  sore  eyes,  and  trembling  hands  that  spill  a  full  cup,  of  which  the  immediate  punishment  is  a  haunted  sleep  and  unrestful  nights.  …”54  Initial  treatments  as  described  by  Osler  at  the  turn  of  the  20th  century  were  focused  on  supportive  care,  including  confinement  to  bed,  cold  baths  to  reduce  fever,  and  judicious  use  of  potassium  bromide,  chloral  hydrate,  hyoscine,  and,  possibly,  opium.20