RT Book, Section
A1 Hartskeerl, Rudy A.
A1 Wagenaar, Jiři F. P.
A2 Kasper, Dennis
A2 Fauci, Anthony
A2 Hauser, Stephen
A2 Longo, Dan
A2 Jameson, J. Larry
A2 Loscalzo, Joseph
SR Print(0)
ID 1120800232
T1 Leptospirosis
T2 Harrison's Principles of Internal Medicine, 19e
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071802154
LK accesspharmacy.mhmedical.com/content.aspx?aid=1120800232
RD 2022/07/04
AB Leptospirosis  is  a  globally  important  zoonotic  disease  whose  apparent  reemergence  is  illustrated  by  recent  outbreaks  on  virtually  all  continents.  The  disease  is  caused  by  pathogenic  Leptospira  species  and  is  characterized  by  a  broad  spectrum  of  clinical  manifestations,  varying  from  asymptomatic  infection  to  fulminant,  fatal  disease.  In  its  mild  form,  leptospirosis  may  present  as  nonspecific  symptoms  such  as  fever,  headache,  and  myalgia.  Severe  leptospirosis,  characterized  by  jaundice,  renal  dysfunction,  and  hemorrhagic  diathesis,  is  often  referred  to  as  Weil’s  syndrome.  With  or  without  jaundice,  severe  pulmonary  hemorrhage  is  increasingly  recognized  as  an  important  presentation  of  severe  disease.