RT Book, Section A1 Bacon, Bruce R. A2 Kasper, Dennis A2 Fauci, Anthony A2 Hauser, Stephen A2 Longo, Dan A2 Jameson, J. Larry A2 Loscalzo, Joseph SR Print(0) ID 1126281714 T1 Cirrhosis and Its Complications T2 Harrison's Principles of Internal Medicine, 19e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071802154 LK accesspharmacy.mhmedical.com/content.aspx?aid=1126281714 RD 2021/04/17 AB Cirrhosis is a condition that is defined histopathologically and has a variety of clinical manifestations and complications, some of which can be life-threatening. In the past, it has been thought that cirrhosis was never reversible; however, it has become apparent that when the underlying insult that has caused the cirrhosis has been removed, there can be reversal of fibrosis. This is most apparent with the successful treatment of chronic hepatitis C; however, reversal of fibrosis is also seen in patients with hemochromatosis who have been successfully treated and in patients with alcoholic liver disease who have discontinued alcohol use.