RT Book, Section
A1 Greenberg, Raymond S.
A2 Greenberg, Raymond S.
SR Print(0)
ID 1108589656
T1 Introduction to Epidemiology
T2 Medical Epidemiology: Population Health and Effective Health Care, 5e
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-182272-5
LK accesspharmacy.mhmedical.com/content.aspx?aid=1108589656
RD 2024/04/20
AB A  53-year-old  previously  healthy  man  visited  his  physician  with  a  chief  complaint  of  a  sore  throat  of  6  weeks’  duration.  The  patient  reported  pain  on  swallowing  but  did  not  have  a  fever,  cough,  or  congestion.  He  did  not  smoke  and  had  an  occasional  glass  of  wine  with  dinner.  A  physical  examination  revealed  a  3-cm  mass  on  the  left  side  of  the  posterior  pharynx  along  with  an  ipsilateral  1-cm  firm,  immovable  cervical  lymph  node.  A  referral  was  made  to  an  otolaryngologist,  who  performed  a  biopsy  yielding  a  diagnosis  of  squamous  cell  carcinoma  of  the  posterior  pharynx.  The  patient  subsequently  underwent  a  complete  surgical  resection  of  the  primary  tumor  and  a  selective  dissection  of  cervical  lymph  nodes,  two  of  six  of  which  had  malignant  cells  present.  Examination  of  the  tumor  specimen  by  situ  hybridization  was  positive  for  human  papillomavirus  (HPV)  type  16.  The  patient  was  treated  additionally  with  external-beam  radiation  therapy,  and  there  was  no  evidence  of  tumor  recurrence  within  the  initial  3  years  after  diagnosis.