RT Book, Section
A1 RICCOBONO, DENISE E.
A1 MONTEAGUDO-CHU, MARICELLE O.
A2 Cohen, Henry
SR Print(0)
ID 1112259650
T1 Vancomycin
T2 Casebook in Clinical Pharmacokinetics and Drug Dosing
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071628358
LK accesspharmacy.mhmedical.com/content.aspx?aid=1112259650
RD 2024/04/25
AB Vancomycin  is  a  glycopeptide  antibiotic,  approved  by  the  FDA  in  1958,  which  is  slowly  bactericidal  against  most  gram-positive  organisms.  It  is  active  against  Staphylococci  (including  penicillin-  and  oxacillin-resistant  strains),  Streptococci,  Enterococci,  and  other  gram-positive  organisms.  It  exerts  its  bactericidal  effect  by  complexing  with  the  D-alanyl-D-alanine  portion  of  the  peptide  precursor  units  on  the  outer  surface  of  the  cell  membrane  and  interferes  with  cell  wall  synthesis.