RT Book, Section
A1 Carroll, Karen C.
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 McKerrow, James H.
A1 Sakanari, Judy A.
SR Print(0)
ID 1114735321
T1 Chlamydia spp.
T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071824989
LK accesspharmacy.mhmedical.com/content.aspx?aid=1114735321
RD 2024/04/16
AB Chlamydiae  that  infect  humans  are  divided  into  three  species,  Chlamydia  trachomatis,  Chlamydia  pneumoniae,  and  Chlamydia  psittaci,  on  the  basis  of  antigenic  composition,  intracellular  inclusions,  sulfadiazine  susceptibility,  and  disease  production.  The  separation  of  the  genus  Chlamydia  into  the  genera  Chlamydia  and  Chlamydophila  was  controversial;  in  this  chapter,  the  three  chlamydiae  that  are  pathogens  of  humans  are  considered  to  be  in  the  genus  Chlamydia  in  keeping  with  publications  that  do  not  support  the  new  taxonomy.  Other  chlamydiae  infect  animals  but  rarely  if  ever  infect  humans.  All  chlamydiae  exhibit  similar  morphologic  features,  share  a  common  group  antigen,  and  multiply  in  the  cytoplasm  of  their  host  cells  by  a  distinctive  developmental  cycle.  The  chlamydiae  can  be  viewed  as  gram-negative  bacteria  that  lack  mechanisms  for  the  production  of  metabolic  energy  and  cannot  synthesize  adenosine  triphosphate  (ATP).  This  restricts  them  to  an  intracellular  existence,  where  the  host  cell  furnishes  energy-rich  intermediates.  Thus,  chlamydiae  are  obligate  intracellular  pathogens.