RT Book, Section A1 Carroll, Karen C. A1 Hobden, Jeffery A. A1 Miller, Steve A1 Morse, Stephen A. A1 Mietzner, Timothy A. A1 Detrick, Barbara A1 Mitchell, Thomas G. A1 McKerrow, James H. A1 Sakanari, Judy A. SR Print(0) ID 1114735759 T1 Antimicrobial Chemotherapy T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071824989 LK accesspharmacy.mhmedical.com/content.aspx?aid=1114735759 RD 2024/04/25 AB Drugs have been used for the treatment of infectious diseases since the 17th century (eg, quinine for malaria, emetine for amebiasis); however, chemotherapy as a science began in the first decade of the 20th century with understanding of the principles of selective toxicity, the specific chemical relationships between microbial pathogens and drugs, the development of drug resistance, and the role of combined therapy. Experiments led to the arsphenamines for syphilis, the first planned chemotherapeutic regimen.